Advances in Cancer Research, Vol. 61 by George F. Vande Woude (ed.), George Klein (ed.)

By George F. Vande Woude (ed.), George Klein (ed.)

Quantity sixty one of "Advances in melanoma examine" contains insurance of the subsequent: molecular methods to melanoma remedy, radiation resistance, melanoma prevention learn trials, mammalian gene amplification, retinoblastoma gene functionality, molecular genetic foundation of breast melanoma, and tumour merchandising by means of okadaic acid classification compounds.

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B. (1976). Cancer Res. 36, 2699. Sporn, M. B. (1991). Cancer Res. 51, 6215-6218. Steinmetz, K. , and Potter, J. D. (1991a). Cancer Causes Control 2, 325-357. Steinmetz, K. , and Potter, J. D. (1991b). Cancer Causes Control 2, 427-442. Stemmermann, G. , and Chyou, P. H. (1990). Dis. Colon Rectum 33, 190194. Taylor, J. A. (1989). A m . J . Epidemiol. 130, 6-13. Thun, M. , Namboodiri, M. , and Heath, C. , Jr. (1991). N . Engl. J . Med. 325, 15931596. S. Food and Drug Administration (1991). Fed. Regkter 56, 60566-60578.

Inherited factors are known to play an important role in breast cancer development in a subgroup of patients; to define the gene alterations responsible for the inheritable predisposition to breast cancer development will be of great importance in clinical management. A genetic alteration results in qualitative or quantitative changes in the protein, encoded by the altered gene; research is being directed at understanding the function of these proteins and how they affect the behavior of cells.

18, 576-591. Muir, C. Cancer Res. 50,644 1-6448. C. National Cancer Institute and NCI Division of Cancer Prevention and Control (1991). S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Bethesda, Maryland. Nayfield, S. , Karp, J. , Ford, L. G . , and Kramer, B. S. Natl. Cancer Imt. 83, 1450-1459. Newmark, H. , and Maheshwari, N. J. Clin. Nutr. 54,209s-214s. Newmark, H. , Wargovich, M. , and Bruce, W. R. (1984). J. Natl. Cancer Inst. 72, 13231325. Nigro, N.

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